This comparison summarizes differences useful for designing and documenting studies. It does not constitute clinical guidance or a recommendation for human use.
| Feature | Ipamorelin | Sermorelin |
|---|---|---|
| Class | GH secretagogue | GHRH analog |
| Receptor | GHS-R1a | GHRH-R |
| Length | Pentapeptide | 29 amino acids |
| Experimental use | GH pulses | Hypothalamic signal |
How to interpret the evidence
Always compare species or cell line, sample size, analytical method, material purity and primary endpoints. Preclinical results should not be automatically extrapolated to humans.