Fundamentos · 7 min

Differences between peptide families

Overview of families: incretin (GLP-1, GIP), regenerative (BPC-157, TB-500), GH secretagogues, neuropeptides and dermatological.

Peptides are grouped by the receptor family they engage or by their historical research context. The main groups relevant to the Peptide Life catalog are outlined below.

Incretin (GLP-1, GIP)

Semaglutide, Tirzepatide and Retatrutide are studied for their activity on GLP-1R and, in dual/triple agonists, on GIPR and GCGR. They are central to metabolic research.

Regenerative

BPC-157 and TB-500 are investigated in preclinical models of angiogenesis, actin dynamics and tissue signaling.

GH secretagogues and GHRH analogs

Ipamorelin, CJC-1295, Tesamorelin and Sermorelin are used to study the GHS-R1a and GHRH-R axes and their downstream effects on IGF-1 and lipid metabolism.

Neuropeptides

Selank and Semax are researched in neurobiological models of GABAergic and BDNF-related signaling.

Dermatological

GHK-Cu and AHK-Cu are copper-binding peptides studied in extracellular matrix and follicular signaling models.